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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RING1
All Species:
9.7
Human Site:
S229
Identified Species:
19.39
UniProt:
Q06587
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06587
NP_002922.2
406
42429
S229
G
V
G
G
G
A
G
S
E
D
S
G
D
R
G
Chimpanzee
Pan troglodytes
NP_001074951
377
39081
S219
G
G
T
L
G
P
P
S
P
P
G
A
P
S
P
Rhesus Macaque
Macaca mulatta
Q8WMN5
377
39081
S219
G
G
T
L
G
P
P
S
P
P
G
A
P
S
P
Dog
Lupus familis
XP_859904
245
27899
L100
K
L
V
S
K
R
S
L
R
P
D
P
N
F
D
Cat
Felis silvestris
Mouse
Mus musculus
O35730
406
42612
S229
G
A
C
G
G
A
G
S
E
D
S
G
D
R
G
Rat
Rattus norvegicus
Q6MGB6
406
42642
S229
G
A
C
G
G
A
G
S
E
D
S
G
D
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506883
131
14948
Chicken
Gallus gallus
XP_422295
336
37573
G191
T
H
S
N
Q
E
A
G
P
S
N
K
R
T
K
Frog
Xenopus laevis
Q66J69
344
38348
R198
E
A
G
P
S
R
K
R
S
R
A
S
E
D
S
Zebra Danio
Brachydanio rerio
Q803I4
336
37521
G191
V
H
S
N
Q
E
A
G
P
S
I
K
R
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB08
435
47237
A246
S
S
S
A
N
S
G
A
S
T
S
A
T
R
M
Honey Bee
Apis mellifera
XP_393984
403
44539
N243
N
S
T
T
P
S
P
N
P
A
N
Q
I
P
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
92.6
45
N.A.
96.5
96.8
N.A.
32
55.9
65.7
55.9
N.A.
39.7
42.1
N.A.
N.A.
Protein Similarity:
100
92.6
92.6
51.9
N.A.
97
97.7
N.A.
32.2
65.7
70.4
66.2
N.A.
51.9
53.9
N.A.
N.A.
P-Site Identity:
100
20
20
0
N.A.
86.6
86.6
N.A.
0
0
6.6
0
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
20
20
13.3
N.A.
86.6
86.6
N.A.
0
6.6
20
0
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
9
0
25
17
9
0
9
9
25
0
0
0
% A
% Cys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
25
9
0
25
9
9
% D
% Glu:
9
0
0
0
0
17
0
0
25
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
42
17
17
25
42
0
34
17
0
0
17
25
0
0
25
% G
% His:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% I
% Lys:
9
0
0
0
9
0
9
0
0
0
0
17
0
0
25
% K
% Leu:
0
9
0
17
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
0
0
17
9
0
0
9
0
0
17
0
9
0
0
% N
% Pro:
0
0
0
9
9
17
25
0
42
25
0
9
17
9
17
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
17
0
9
9
9
0
0
17
34
0
% R
% Ser:
9
17
25
9
9
17
9
42
17
17
34
9
0
17
9
% S
% Thr:
9
0
25
9
0
0
0
0
0
9
0
0
9
17
0
% T
% Val:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _